Description
Product Characteristics: For the quantitative determination of human N-myc proto-oncogene protein (MYCN) concentrations in serum, plasma, tissue homogenates, cell lysates.
Target Information: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008]